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In double-blind, placebo-controlled trials, daily application of GHK-Cu cream at 3% concentration for 12 weeks produced a 70% increase in skin collagen thickness as measured by ultrasound imaging, a 40% increase in skin elasticity, and visible reduction in fine lines and wrinkles

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10.1016/j.chemphyslip.2009.03.008 33 EsterbauerH.EcklP.OrtnerA

(January 2001)

Levels of SQSTM1/p62 expression in Kupffer cells, stellate cells, sinusoidal endothelial cells, and cholangiocytes of severely steatotic livers were 14%, 24%, 33%, and 43% of values in mildly steatotic livers, respectively